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How Does Malarone Work? Malarone tablets contain two active ingredients, proguanil hydrochloride and atovaquone. Malaria occurs when the plasmodium parasite enters the bloodstream and starts to reproduce. Proguanil works by inhibiting the parasite’s ability to reproduce. Proguanil blocks the action of the dihydrofolate reductase enzyme that helps the parasite to reproduce and multiply. It prevents the formation of any new genetic material forming within the parasite, inhibiting reproduction. Atovaquone works similarly to proguanil. It hinders the production of new genetic material from inside the malaria parasite, resulting in its inability to reproduce.
Malarone Warnings Malarone is unsuitable for you if you: Are allergic to the ingredients. Have liver or kidney problems. Are pregnant or breastfeeding.
How to Take Malarone You should take one tablet every day at roughly the same time daily. Take 1 – 2 days before entering a high-risk zone and continue for seven days after leaving the topical area. Swallow Malarone with or after food or milk. Malarone remains effective with a moderate alcohol intake. In the event of vomiting within 1 hour of taking Malarone, repeat the dose.
Malarone Ingredients Malarone tablets contain two active ingredients Proguanil Hydrochloride and Atovaquone. Each capsule contains poloxamer 188, microcrystalline cellulose, hydroxypropyl cellulose, povidone K30, sodium starch glycolate (Type A), and magnesium stearate. The coating is made of hypromellose, titanium dioxide (E171), and iron oxide red (E172), macrogol 400, and polyethylene glycol 8000.
Side Effects of Using Malarone When used to prevent malaria, Malarone tablets rarely cause side effects. If you experience any, the side effects include: Coughing. Diarrhoea. Dizziness. Headache. Loss of appetite. Mouth sores. Nausea. Stomach pain. Vomiting. Weakness.